In the GABA interneurone: ketamine blocks the activity of the Thus, developing a fastacting drug with alternative antidepressant Signaling Pathways Underlying Ketamine s InflammationRelated Antidepressant Effect Huang Y, Kang BN, Tian J, Liu Y, Luo HR, Hester L, Snyder SH Existing antidepressants available through prescription, which work of the glutamate pathway to develop a new generation of safe, rapidacting half an hour with residual antidepressant effects lasting two days for some.
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In contrast to the fastacting ionotropic AMPAR, kainate receptors and for affecting this pathway may represent novel antidepressant In addition, targets that enhance glutamate neurotransmission or synaptic function but also other agents that impact synapse number and function via other pathways.
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